Is Merck & Co. Inc. (MRK) Stock Undervalued or Overvalued?
Trailing-twelve-month multiples vs Healthcare sector peers in our coverage
MRK trades at 16.8× TTM earnings — a 44% discount to its Healthcare sector average of 29.8× in our coverage.
The Numbers
P/E (TTM)
16.8×
Sector avg: 29.8×
P/S (TTM)
4.9×
Sector avg: 7.0×
Market Cap
$314.75B
EPS (TTM): $7.57
Revenue (TTM)
$64.23B
Net income: $19.04B
Healthcare Peer Comparison
How MRK's multiples stack up against sector peers we cover. Click any peer for its own valuation breakdown.
Is the Discount Justified?
July 6, 2026Merck's P/E ratio of 16.7x, a notable discount to the healthcare sector average of 27.2x, is primarily influenced by the impending patent expiration of its top-selling cancer drug, Keytruda, in late 2028. Keytruda has been a significant revenue driver, accounting for nearly half of the company's total sales. To mitigate this "patent cliff," Merck is aggressively expanding its pipeline through strategic acquisitions and developing new formulations, such as a subcutaneous Keytruda, which could extend its market exclusivity. The company projects new growth drivers to generate over $70 billion in annual revenue by the mid-2030s. The current valuation reflects market concerns about the revenue gap post-Keytruda, despite proactive diversification efforts.
Frequently Asked Questions
Is MRK overvalued or undervalued?
What does the P/E ratio tell you?
Why compare against the sector average?
Is a cheap stock automatically a good buy?
Methodology
Multiples are computed from trailing-twelve-month fundamentals (from company filings) and the latest share price: P/E is price ÷ diluted EPS, and P/S is market cap ÷ revenue. Sector averages use the Healthcare names in our 50-stock coverage with positive earnings — a deliberately like-for-like, if imperfect, benchmark.
Stocks with negative trailing earnings are compared on price-to-sales instead. Multiples update with prices and fundamentals; AI context refreshes weekly.
Not Financial Advice
This page is for education and information only. Indicators are mechanical calculations, AI commentary can contain errors, and nothing here is a recommendation to buy or sell any security. Do your own research and consider consulting a qualified financial advisor. See our full disclaimer.
Keep Digging on MRK
Merck & Co. Inc. Overview
Price, chart, analysis & financials
MRK: Overbought or Oversold?
Updated daily
MRK: Why Is It Moving?
Updated daily
MRK: Price Prediction
Updated daily
Same question, Healthcare peers